Performance of LVEF, the Global Registry of Acute Coronary Events (GRACE), Thrombolysis in Myocardial Infarction (TIMI) and ECG scores to predict 24-month all-cause mortality were analyzed. ECG score was developed to predict LVEF < 40%. LV ejection fraction (LVEF) was assessed by echocardiography within 72 h after the first triage ECG acquisition there was no coronary intervention in between. GRACE score should be used as risk stratification modality in clinical decision making for the management of NSTE-ACS.īackground: Few studies have characterized electrocardiography (ECG) patterns correlated with left ventricular (LV) systolic dysfunction in patients with non-ST segment elevation acute coronary syndrome (NSTE-ACS).Objectives: This study aims to develop ECG pattern-derived scores to predict LV systolic dysfunction in NSTE-ACS patients.Methods: A total of 466 patients with NSTE-ACS were retrospectively enrolled. The AUC for the TIMI score was 0.781 with the optimal cut-off value of 4 with sensitivity of 75.0% and specificity of 67.6%.Ĭonclusion: The GRACE score has high discriminating strength for predicting in-hospital mortality after NSTE-ACS. AUC for the GRACE score was 0.851 with the optimal cut-off value of 150 with sensitivity of 68.8% and specificity of 84.9%. Mean GRACE and TIMI score were 120.19☓3.17 and 3.18☐.85 respectively. Results: A total of 300 patients were included, out of which 76.7%(230) were male and mean age was 58.04☑0.71 years. The receiver operating characteristic (ROC) curves analysis was performed and area under the curve (AUC) was obtained as indicative of predictive value for both scores. GRACE and TIMI score were obtained and in-hospital mortality was recorded. Methodology: This study included prospectively recruited cohort of patients presented to a tertiary care cardiac center of Karachi, Pakistan who were diagnosed with NSTE-ACS. Objectives: To compare the predictive value of TIMI and GRACE score for predicting in-hospital outcomes after non-ST elevation acute coronary syndrome (NSTE-ACS).
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